Looks like the TweetDeck crew have a money making plan and it consists of branding their Twitter client as reported by ReadWriteWeb. Their first skinnable version is Blink182 and not only includes visuals but alerts from the band.
It reminds me of the Pandora.com approach to advertising where the whole page becomes an advert. Pandora have more whitespace to play with compared to TweetDeck, but on the flip side people spend less time in Pandora.
I’m not sure how I feel about my client app being branded - it does feel a little strange - but I guess I could get used to it. It would be great if I could get exclusive content according to the skin I installed. For example, with the Blink 182 skin I get interviews with the band or a video download from a recent concert. Getting content could be obvious but also be in the form of Easter eggs which make the user explore the app more to unlock the exclusive content.